Oellerich Lab
Publications

Alsouri, Saed; Ambrose, Ashley; Mougios, Nikolaos; Paglilla, Nadia; Mayr, Florian; Choi, Kate; Loeber, Jens; Chapuy, Björn; Haeupl, Björn; Opazo, Felipe; Oellerich, Thomas; Gold, Michael; Engelke, Michael (2024): Actinin-4 controls survival signaling in B cells by limiting the lateral mobility of B-cell antigen receptors. In: European Journal of Immunology 54 (3), e2350774. DOI: 10.1002/eji.202350774.

Choi, Jaewoo; Ceribelli, Michele; Phelan, James D.; Häupl, Björn; Da Huang, Wei; Wright, George W.; Hsiao, Tony; Morris, Vivian; Ciccarese, Francesco; Wang, Boya; Corcoran, Sean; Scheich, Sebastian; Yu, Xin; Xu, Weihong; Yang, Yandan; Zhao, Hong; Zhou, Joyce; Zhang, Grace; Muppidi, Jagan; Inghirami, Giorgio G.; Oellerich, Thomas; Wilson, Wyndham H.; Thomas, Craig J.; Staudt, Louis M. (2024): Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas. In: Cancer Cell 42 (5), 833-849.e12. DOI: 10.1016/j.ccell.2024.04.007.

Corcoran, Sean R.; Phelan, James D.; Choi, Jaewoo; Shevchenko, Galina; Fenner, Rachel E.; Yu, Xin; Scheich, Sebastian; Hsiao, Tony; Morris, Vivian M.; Papachristou, Evangelia K.; Kishore, Kamal; D'Santos, Clive S.; Ji, Yanlong; Pittaluga, Stefania; Wright, George W.; Urlaub, Henning; Pan, Kuan-Ting; Oellerich, Thomas; Muppidi, Jagan; Hodson, Daniel J.; Staudt, Louis M. (2024): Molecular Determinants of Sensitivity to Polatuzumab Vedotin in Diffuse Large B Cell Lymphoma. In: Cancer Discovery. DOI: 10.1158/2159-8290.CD-23-0802.

Enssle, Julius C.; Campe, Julia; Moter, Alina; Voit, Isabel; Gessner, Alec; Yu, Weijia; Wolf, Sebastian; Steffen, Björn; Serve, Hubert; Bremm, Melanie; Huenecke, Sabine; Lohoff, Michael; Vehreschild, Maria; Rabenau, Holger F.; Widera, Marek; Ciesek, Sandra; Oellerich, Thomas; Imkeller, Katharina; Rieger, Michael A.; Metzler, Ivana von; Ullrich, Evelyn (2024): Cytokine-responsive T- and NK-cells portray SARS-CoV-2 vaccine-responders and infection in multiple myeloma patients. In: Leukemia 38 (1), S. 168–180. DOI: 10.1038/s41375-023-02070-0.

Felipe Fumero, Eloísa; Walter, Carolin; Frenz, Joris Maximillian; Seifert, Franca; Alla, Vijay; Hennig, Thorben; Angenendt, Linus; Hartmann, Wolfgang; Wolf, Sebastian; Serve, Hubert; Oellerich, Thomas; Lenz, Georg; Müller-Tidow, Carsten; Schliemann, Christoph; Huber, Otmar; Dugas, Martin; Mann, Matthias; Jayavelu, Ashok Kumar; Mikesch, Jan-Henrik; Arteaga, Maria Francisca (2024): Epigenetic control over the cell-intrinsic immune response antagonizes self-renewal in acute myeloid leukemia. In: Blood 143 (22), S. 2284–2299. DOI: 10.1182/blood.2023021640.

Mayr, Florian; Kruse, Vanessa; Fuhrmann, Dominik C.; Wolf, Sebastian; Löber, Jens; Alsouri, Saed; Paglilla, Nadia; Lee, Kwang; Chapuy, Björn; Brüne, Bernhard; Zenz, Thorsten; Häupl, Björn; Oellerich, Thomas; Engelke, Michael (2024): SH2 domain-containing inositol 5-phosphatases support the survival of Burkitt lymphoma cells by promoting energy metabolism. In: Haematologica 109 (5), S. 1445–1459. DOI: 10.3324/haematol.2023.283663.

Phelan, James D.; Scheich, Sebastian; Choi, Jaewoo; Wright, George W.; Häupl, Björn; Young, Ryan M.; Rieke, Sara A.; Pape, Martine; Ji, Yanlong; Urlaub, Henning; Bolomsky, Arnold; Doebele, Carmen; Zindel, Alena; Wotapek, Tanja; Kasbekar, Monica; Collinge, Brett; Da Huang, Wei; Coulibaly, Zana A.; Morris, Vivian M.; Zhuang, Xiaoxuan; Enssle, Julius C.; Yu, Xin; Xu, Weihong; Yang, Yandan; Zhao, Hong; Wang, Zhuo; Tran, Andy D.; Shoemaker, Christopher J.; Shevchenko, Galina; Hodson, Daniel J.; Shaffer, Arthur L. 3rd; Staudt, Louis M.; Oellerich, Thomas (2024): Response to Bruton's tyrosine kinase inhibitors in aggressive lymphomas linked to chronic selective autophagy. In: Cancer Cell 42 (2), 238-252.e9. DOI: 10.1016/j.ccell.2023.12.019.

Alshamleh, Islam; Kurrle, Nina; Makowka, Philipp; Bhayadia, Raj; Kumar, Rahul; Süsser, Sebastian; Seibert, Marcel; Ludig, Damian; Wolf, Sebastian; Koschade, Sebastian E.; Stoschek, Karoline; Kreitz, Johanna; Fuhrmann, Dominik C.; Toenges, Rosa; Notaro, Marco; Comoglio, Federico; Schuringa, Jan Jacob; Berg, Tobias; Brüne, Bernhard; Krause, Daniela S.; Klusmann, Jan-Henning; Oellerich, Thomas; Schnütgen, Frank; Schwalbe, Harald; Serve, Hubert (2023): PDP1 is a key metabolic gatekeeper and modulator of drug resistance in FLT3-ITD-positive acute myeloid leukemia. In: Leukemia 37 (12), S. 2367–2382. DOI: 10.1038/s41375-023-02041-5.

Maier, Daniel; Vehreschild, Jörg Janne; Uhl, Barbara; Meyer, Sandra; Berger-Thürmel, Karin; Boerries, Melanie; Braren, Rickmer; Grünwald, Viktor; Hadaschik, Boris; Palm, Stefan; Singer, Susanne; Stuschke, Martin; Juárez, David; Delpy, Pierre; Lambarki, Mohamed; Hummel, Michael; Engels, Cäcilia; Andreas, Stefanie; Gökbuget, Nicola; Ihrig, Kristina; Burock, Susen; Keune, Dietmar; Eggert, Angelika; Keilholz, Ulrich; Schulz, Hagen; Büttner, Daniel; Löck, Steffen; Krause, Mechthild; Esins, Mirko; Ressing, Frank; Schuler, Martin; Brandts, Christian; Brucker, Daniel P.; Husmann, Gabriele; Oellerich, Thomas; Metzger, Patrick; Voigt, Frederik; Illert, Anna L.; Theobald, Matthias; Kindler, Thomas; Sudhof, Ursula; Reckmann, Achim; Schwinghammer, Felix; Nasseh, Daniel; Weichert, Wilko; Bergwelt-Baildon, Michael von; Bitzer, Michael; Malek, Nisar; Öner, Öznur; Schulze-Osthoff, Klaus; Bartels, Stefan; Haier, Jörg; Ammann, Raimund; Schmidt, Anja Franziska; Guenther, Bernd; Janning, Melanie; Kasper, Bernd; Loges, Sonja; Stilgenbauer, Stephan; Kuhn, Peter; Tausch, Eugen; Runow, Silvana; Kerscher, Alexander; Neumann, Michael; Breu, Martin; Lablans, Martin; Serve, Hubert (2023): Profile of the multicenter cohort of the German Cancer Consortium's Clinical Communication Platform. In: European Journal of Epidemiology 38 (5), S. 573–586. DOI: 10.1007/s10654-023-00990-w.

Mandal, Ranadip; Raab, Monika; Rödel, Franz; Krämer, Andrea; Kostova, Izabela; Peña-Llopis, Samuel; Medici, Gioele; Häupl, Björn; Oellerich, Thomas; Gasimli, Khayal; Sanhaji, Mourad; Becker, Sven; Strebhardt, Klaus (2023): Correction: The non-apoptotic function of Caspase-8 in negatively regulating the CDK9-mediated Ser2 phosphorylation of RNA polymerase II in cervical cancer. In: Cellular and Molecular Life Sciences : CMLS 80 (3), S. 64. DOI: 10.1007/s00018-023-04686-y.

Merk-Ahmad, Katrin; Bein, Julia; Scharf, Sonja; Schäfer, Hendrik; Bexte, Tobias; Ullrich, Evelyn; Loth, Andreas G.; Flinner, Nadine; Senff, Tina; Schneider, Olga; Hansmann, Martin-Leo; Piel, Matthieu; Häupl, Björn; Oellerich, Thomas; Donnadieu, Emmanuel; Hartmann, Sylvia (2023): The RHOA Mutation G17V Does Not Lead to Increased Migration of Human Malignant T Cells but Is Associated with Matrix Remodelling. In: Cancers 15 (12). DOI: 10.3390/cancers15123226.

Rösler, Wiebke; Altenbuchinger, Michael; Baeßler, Bettina; Beissbarth, Tim; Beutel, Gernot; Bock, Robert; Bubnoff, Nikolas von; Eckardt, Jan-Niklas; Foersch, Sebastian; Loeffler, Chiara M. L.; Middeke, Jan Moritz; Mueller, Martha-Lena; Oellerich, Thomas; Risse, Benjamin; Scherag, André; Schliemann, Christoph; Scholz, Markus; Spang, Rainer; Thielscher, Christian; Tsoukakis, Ioannis; Kather, Jakob Nikolas (2023): An overview and a roadmap for artificial intelligence in hematology and oncology. In: Journal of Cancer Research and Clinical Oncology 149 (10), S. 7997–8006. DOI: 10.1007/s00432-023-04667-5.

Scheich, Sebastian; Chen, Jiji; Liu, Jiamin; Schnütgen, Frank; Enssle, Julius C.; Ceribelli, Michele; Thomas, Craig J.; Choi, Jaewoo; Morris, Vivian; Hsiao, Tony; Nguyen, Hang; Wang, Boya; Bolomsky, Arnold; Phelan, James D.; Corcoran, Sean; Urlaub, Henning; Young, Ryan M.; Häupl, Björn; Wright, George W.; Da Huang, Wei; Ji, Yanlong; Yu, Xin; Xu, Weihong; Yang, Yandan; Zhao, Hong; Muppidi, Jagan; Pan, Kuan-Ting; Oellerich, Thomas; Staudt, Louis M. (2023): Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas. In: Cancer Discovery 13 (8), S. 1862–1883. DOI: 10.1158/2159-8290.CD-22-1401.

vom Stein, Alexander F.; Rebollido-Rios, Rocio; Lukas, Anna; Koch, Maximilian; Lom, Anton von; Reinartz, Sebastian; Bachurski, Daniel; Rose, France; Bozek, Katarzyna; Abdallah, Ali T.; Kohlhas, Viktoria; Saggau, Julia; Zölzer, Rebekka; Zhao, Yue; Bruns, Christiane; Bröckelmann, Paul J.; Lohneis, Philipp; Büttner, Reinhard; Häupl, Björn; Oellerich, Thomas; Nguyen, Phuong-Hien; Hallek, Michael (2023): LYN kinase programs stromal fibroblasts to facilitate leukemic survival via regulation of c-JUN and THBS1. In: Nature Communications 14 (1), S. 1330. DOI: 10.1038/s41467-023-36824-2.

Zhou, Fengbiao; Aroua, Nesrine; Liu, Yi; Rohde, Christian; Cheng, Jingdong; Wirth, Anna-Katharina; Fijalkowska, Daria; Göllner, Stefanie; Lotze, Michelle; Yun, Haiyang; Yu, Xiaobing; Pabst, Caroline; Sauer, Tim; Oellerich, Thomas; Serve, Hubert; Röllig, Christoph; Bornhäuser, Martin; Thiede, Christian; Baldus, Claudia; Frye, Michaela; Raffel, Simon; Krijgsveld, Jeroen; Jeremias, Irmela; Beckmann, Roland; Trumpp, Andreas; Müller-Tidow, Carsten (2023): A Dynamic rRNA Ribomethylome Drives Stemness in Acute Myeloid Leukemia. In: Cancer Discovery 13 (2), S. 332–347. DOI: 10.1158/2159-8290.CD-22-0210.

Bein, Julia; Flinner, Nadine; Häupl, Björn; Mathur, Aastha; Schneider, Olga; Abu-Ayyad, Marwa; Hansmann, Martin-Leo; Piel, Matthieu; Oellerich, Thomas; Hartmann, Sylvia (2022): T-cell-derived Hodgkin lymphoma has motility characteristics intermediate between Hodgkin and anaplastic large cell lymphoma. In: Journal of Cellular and Molecular Medicine 26 (12), S. 3495–3505. DOI: 10.1111/jcmm.17389.

Elakad, Omar; Häupl, Björn; Labitzky, Vera; Yao, Sha; Küffer, Stefan; Hammerstein-Equord, Alexander von; Danner, Bernhard C.; Jücker, Manfred; Urlaub, Henning; Lange, Tobias; Ströbel, Philipp; Oellerich, Thomas; Bohnenberger, Hanibal (2022): Activation of CD44/PAK1/AKT signaling promotes resistance to FGFR1 inhibition in squamous-cell lung cancer. In: NPJ Precision Oncology 6 (1), S. 52. DOI: 10.1038/s41698-022-00296-2.

Fang, Pan; Ji, Yanlong; Oellerich, Thomas; Urlaub, Henning; Pan, Kuan-Ting (2022): Strategies for Proteome-Wide Quantification of Glycosylation Macro- and Micro-Heterogeneity. In: International Journal of Molecular Sciences 23 (3). DOI: 10.3390/ijms23031609.

Jayavelu, Ashok Kumar; Wolf, Sebastian; Buettner, Florian; Alexe, Gabriela; Häupl, Björn; Comoglio, Federico; Schneider, Constanze; Doebele, Carmen; Fuhrmann, Dominik C.; Wagner, Sebastian; Donato, Elisa; Andresen, Carolin; Wilke, Anne C.; Zindel, Alena; Jahn, Dominique; Splettstoesser, Bianca; Plessmann, Uwe; Münch, Silvia; Abou-El-Ardat, Khali; Makowka, Philipp; Acker, Fabian; Enssle, Julius C.; Cremer, Anjali; Schnütgen, Frank; Kurrle, Nina; Chapuy, Björn; Löber, Jens; Hartmann, Sylvia; Wild, Peter J.; Wittig, Ilka; Hübschmann, Daniel; Kaderali, Lars; Cox, Jürgen; Brüne, Bernhard; Röllig, Christoph; Thiede, Christian; Steffen, Björn; Bornhäuser, Martin; Trumpp, Andreas; Urlaub, Henning; Stegmaier, Kimberly; Serve, Hubert; Mann, Matthias; Oellerich, Thomas (2022): The proteogenomic subtypes of acute myeloid leukemia. In: Cancer Cell 40 (3), 301-317.e12. DOI: 10.1016/j.ccell.2022.02.006.

Kubo, Satoshi; Kataria, Rhea; Yao, Yikun; Gabrielski, Justin Q.; Zheng, Lixin; Markowitz, Tovah E.; Chan, Waipan; Song, Jian; Boddapati, Arun K.; Saeki, Keita; Häupl, Björn; Park, Ann Y.; Cheng, Yan H.; Cui, Jing; Oellerich, Thomas; Lenardo, Michael J. (2022): Early B cell factor 4 modulates FAS-mediated apoptosis and promotes cytotoxic function in human immune cells. In: Proceedings of the National Academy of Sciences of the United States of America 119 (33), e2208522119. DOI: 10.1073/pnas.2208522119.

Mandal, Ranadip; Raab, Monika; Rödel, Franz; Krämer, Andrea; Kostova, Izabela; Peña-Llopis, Samuel; Häupl, Björn; Oellerich, Thomas; Gasimli, Khayal; Sanhaji, Mourad; Becker, Sven; Strebhardt, Klaus (2022): The non-apoptotic function of Caspase-8 in negatively regulating the CDK9-mediated Ser2 phosphorylation of RNA polymerase II in cervical cancer. In: Cellular and Molecular Life Sciences : CMLS 79 (12), S. 597. DOI: 10.1007/s00018-022-04598-3.

Nicolas, Adele M.; Pesic, Marina; Engel, Esther; Ziegler, Paul K.; Diefenhardt, Markus; Kennel, Kilian B.; Buettner, Florian; Conche, Claire; Petrocelli, Valentina; Elwakeel, Eiman; Weigert, Andreas; Zinoveva, Anna; Fleischmann, Maximilian; Häupl, Björn; Karakütük, Cem; Bohnenberger, Hanibal; Mosa, Mohammed H.; Kaderali, Lars; Gaedcke, Jochen; Ghadimi, Michael; Rödel, Franz; Arkan, Melek C.; Oellerich, Thomas; Rödel, Claus; Fokas, Emmanouil; Greten, Florian R. (2022): Inflammatory fibroblasts mediate resistance to neoadjuvant therapy in rectal cancer. In: Cancer Cell 40 (2), 168-184.e13. DOI: 10.1016/j.ccell.2022.01.004.

Phelan, James D.; Oellerich, Thomas (2022): BCL10 Mutants: Architects of Oncogenic Signaling Provide a Blueprint for Precision Medicine. In: Cancer Discovery 12 (8), S. 1844–1846. DOI: 10.1158/2159-8290.CD-22-0614.

Richter, Annika; Fichtner, Alexander; Joost, Jasmin; Brockmeyer, Philipp; Kauffmann, Philipp; Schliephake, Henning; Hammerstein-Equord, Alexander; Kueffer, Stefan; Urlaub, Henning; Oellerich, Thomas; Ströbel, Philipp; Bohnenberger, Hanibal; Bremmer, Felix (2022): Quantitative proteomics identifies biomarkers to distinguish pulmonary from head and neck squamous cell carcinomas by immunohistochemistry. In: The Journal of Pathology. Clinical Research 8 (1), S. 33–47. DOI: 10.1002/cjp2.244.

Wilke, Anne C.; Doebele, Carmen; Zindel, Alena; Lee, Kwang Seok; Rieke, Sara A.; Ceribelli, Michele; Comoglio, Federico; Phelan, James D.; Wang, James Q.; Pikman, Yana; Jahn, Dominique; Häupl, Björn; Schneider, Constanze; Scheich, Sebastian; Tosto, Frances A.; Bohnenberger, Hanibal; Stauder, Philipp; Schnütgen, Frank; Slabicki, Mikolaj; Coulibaly, Zana A.; Wolf, Sebastian; Bojarczuk, Kamil; Chapuy, Björn; Brandts, Christian H.; Stroebel, Philipp; Lewis, Caroline A.; Engelke, Michael; Xu, Xincheng; Kim, Hahn; Dang, Thanh Hung; Schmitz, Roland; Hodson, Daniel J.; Stegmaier, Kimberly; Urlaub, Henning; Serve, Hubert; Schmitt, Clemens A.; Kreuz, Fernando; Knittel, Gero; Rabinowitz, Joshua D.; Reinhardt, Hans Christian; Vander Heiden, Matthew G.; Thomas, Craig; Staudt, Louis M.; Zenz, Thorsten; Oellerich, Thomas (2022): SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma. In: Blood 139 (4), S. 538–553. DOI: 10.1182/blood.2021012081.

Yang, Yandan*; Bolomsky, Arnold*; Oellerich, Thomas*; Chen, Ping*; Ceribelli, Michele; Häupl, Björn; Wright, George W.; Phelan, James D.; Da Huang, Wei; Lord, James W.; van Winkle, Callie K.; Yu, Xin; Wisniewski, Jan; Wang, James Q.; Tosto, Frances A.; Beck, Erin; Wilson, Kelli; McKnight, Crystal; Travers, Jameson; Klumpp-Thomas, Carleen; Smith, Grace A.; Pittaluga, Stefania; Maric, Irina; Kazandjian, Dickran; Thomas, Craig J.; Young, Ryan M. (2022): Oncogenic RAS commandeers amino acid sensing machinery to aberrantly activate mTORC1 in multiple myeloma. In: Nature Communications 13 (1), S. 5469. DOI: 10.1038/s41467-022-33142-x. (*Equal Contribution)

Yang, Yandan; Bolomsky, Arnold; Oellerich, Thomas; Chen, Ping; Ceribelli, Michele; Häupl, Björn; Wright, George W.; Phelan, James D.; Da Huang, Wei; Lord, James W.; van Winkle, Callie K.; Yu, Xin; Wisniewski, Jan; Wang, James Q.; Tosto, Frances A.; Beck, Erin; Wilson, Kelli; McKnight, Crystal; Travers, Jameson; Klumpp-Thomas, Carleen; Smith, Grace A.; Pittaluga, Stefania; Maric, Irina; Kazandjian, Dickran; Thomas, Craig J.; Young, Ryan M. (2022): Publisher Correction: Oncogenic RAS commandeers amino acid sensing machinery to aberrantly activate mTORC1 in multiple myeloma. In: Nature Communications 13 (1), S. 5830. DOI: 10.1038/s41467-022-33618-w.

Yao, Yikun; Kim, Girak; Shafer, Samantha; Chen, Zuojia; Kubo, Satoshi; Ji, Yanlong; Luo, Jialie; Yang, Weiming; Perner, Sebastian P.; Kanellopoulou, Chrysi; Park, Ann Y.; Jiang, Ping; Li, Jian; Baris, Safa; Aydiner, Elif Karakoc; Ertem, Deniz; Mulder, Daniel J.; Warner, Neil; Griffiths, Anne M.; Topf-Olivestone, Chani; Kori, Michal; Werner, Lael; Ouahed, Jodie; Field, Michael; Liu, Chengyu; Schwarz, Benjamin; Bosio, Catharine M.; Ganesan, Sundar; Song, Jian; Urlaub, Henning; Oellerich, Thomas; Malaker, Stacy A.; Zheng, Lixin; Bertozzi, Carolyn R.; Zhang, Yu; Matthews, Helen; Montgomery, Will; Shih, Han-Yu; Jiang, Jiansheng; Jones, Marcus; Baras, Aris; Shuldiner, Alan; Gonzaga-Jauregui, Claudia; Snapper, Scott B.; Muise, Aleixo M.; Shouval, Dror S.; Ozen, Ahmet; Pan, Kuan-Ting; Wu, Chuan; Lenardo, Michael J. (2022): Mucus sialylation determines intestinal host-commensal homeostasis. In: Cell 185 (7), 1172-1188.e28. DOI: 10.1016/j.cell.2022.02.013.

Cui, Chunhong; Liu, Yi; Gerloff, Dennis; Rohde, Christian; Pauli, Cornelius; Köhn, Marcel; Misiak, Danny; Oellerich, Thomas; Schwartz, Schraga; Schmidt, Lars-Henning; Wiewrodt, Rainer; Marra, Alessandro; Hillejan, Ludger; Bartel, Frank; Wickenhauser, Claudia; Hüttelmaier, Stefan; Göllner, Stefanie; Zhou, Fengbiao; Edemir, Bayram; Müller-Tidow, Carsten (2021): NOP10 predicts lung cancer prognosis and its associated small nucleolar RNAs drive proliferation and migration. In: Oncogene 40 (5), S. 909–921. DOI: 10.1038/s41388-020-01570-y.

Fang, Pan; Ji, Yanlong; Silbern, Ivan; Viner, Rosa; Oellerich, Thomas; Pan, Kuan-Ting; Urlaub, Henning (2021): Evaluation and Optimization of High-Field Asymmetric Waveform Ion-Mobility Spectrometry for Multiplexed Quantitative Site-Specific N-Glycoproteomics. In: Analytical Chemistry. DOI: 10.1021/acs.analchem.1c00802.

Gong, Chun; Krupka, Joanna A.; Gao, Jie; Grigoropoulos, Nicholas F.; Giotopoulos, George; Asby, Ryan; Screen, Michael; Usheva, Zelvera; Cucco, Francesco; Barrans, Sharon; Painter, Daniel; Zaini, Nurmahirah Binte Mohammed; Haupl, Björn; Bornelöv, Susanne; Ruiz De Los Mozos, Igor; Meng, Wei; Zhou, Peixun; Blain, Alex E.; Forde, Sorcha; Matthews, Jamie; Khim Tan, Michelle Guet; Burke, G. A. Amos; Sze, Siu Kwan; Beer, Philip; Burton, Cathy; Campbell, Peter; Rand, Vikki; Turner, Suzanne D.; Ule, Jernej; Roman, Eve; Tooze, Reuben; Oellerich, Thomas; Huntly, Brian J.; Turner, Martin; Du, Ming-Qing; Samarajiwa, Shamith A.; Hodson, Daniel J. (2021): Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis. In: Molecular Cell 81 (19), 4059-4075.e11. DOI: 10.1016/j.molcel.2021.07.041.

Malkomes, Patrizia; Lunger, Ilaria; Oppermann, Elsie; Abou-El-Ardat, Khalil; Oellerich, Thomas; Günther, Stefan; Canbulat, Can; Bothur, Sabrina; Schnütgen, Frank; Yu, Weijia; Wingert, Susanne; Haetscher, Nadine; Catapano, Claudia; Dietz, Marina S.; Heilemann, Mike; Kvasnicka, Hans-Michael; Holzer, Katharina; Serve, Hubert; Bechstein, Wolf Otto; Rieger, Michael A. (2021): Transglutaminase 2 promotes tumorigenicity of colon cancer cells by inactivation of the tumor suppressor p53. In: Oncogene 40 (25), S. 4352–4367. DOI: 10.1038/s41388-021-01847-w.

Rothenburger, Tamara; Thomas, Dominique; Schreiber, Yannick; Wratil, Paul R.; Pflantz, Tamara; Knecht, Kirsten; Digianantonio, Katie; Temple, Joshua; Schneider, Constanze; Baldauf, Hanna-Mari; McLaughlin, Katie-May; Rothweiler, Florian; Bilen, Berna; Farmand, Samira; Bojkova, Denisa; Costa, Rui; Ferreirós, Nerea; Geisslinger, Gerd; Oellerich, Thomas; Xiong, Yong; Keppler, Oliver T.; Wass, Mark N.; Michaelis, Martin; Cinatl, Jindrich, JR (2021): Differences between intrinsic and acquired nucleoside analogue resistance in acute myeloid leukaemia cells. In: Journal of Experimental & Clinical Cancer Research : CR 40 (1), S. 317. DOI: 10.1186/s13046-021-02093-4.

Schneider, Lucas; Herkt, Stefanie; Wang, Lei; Feld, Christine; Wesely, Josephine; Kuvardina, Olga N.; Meyer, Annekarin; Oellerich, Thomas; Häupl, Björn; Seifried, Erhard; Bonig, Halvard; Lausen, Joern (2021): PRMT6 activates cyclin D1 expression in conjunction with the transcription factor LEF1. In: Oncogenesis 10 (5), S. 42. DOI: 10.1038/s41389-021-00332-z.

Shaffer, Arthur L. 3rd; Phelan, James D.; Wang, James Q.; Huang, DaWei; Wright, George W.; Kasbekar, Monica; Choi, Jaewoo; Young, Ryan M.; Webster, Daniel E.; Yang, Yandan; Zhao, Hong; Yu, Xin; Xu, Weihong; Roulland, Sandrine; Ceribelli, Michele; Zhang, Xiaohu; Wilson, Kelli M.; Chen, Lu; McKnight, Crystal; Klumpp-Thomas, Carleen; Thomas, Craig J.; Häupl, Björn; Oellerich, Thomas; Rae, Zachary; Kelly, Michael C.; Ahn, Inhye E.; Sun, Clare; Gaglione, Erika M.; Wilson, Wyndham H.; Wiestner, Adrian; Staudt, Louis M. (2021): Overcoming Acquired Epigenetic Resistance to BTK Inhibitors. In: Blood Cancer Discovery 2 (6), S. 630–647. DOI: 10.1158/2643-3230.BCD-21-0063.

Choi, Jaewoo; Phelan, James D.; Wright, George W.; Häupl, Björn; Da Huang, Wei; Shaffer, Arthur L. 3rd; Young, Ryan M.; Wang, Zhuo; Zhao, Hong; Yu, Xin; Oellerich, Thomas; Staudt, Louis M. (2020): Regulation of B cell receptor-dependent NF-κB signaling by the tumor suppressor KLHL14. In: Proceedings of the National Academy of Sciences of the United States of America 117 (11), S. 6092–6102. DOI: 10.1073/pnas.1921187117.

Cremer, Anjali; Ellegast, Jana M.; Alexe, Gabriela; Frank, Elizabeth S.; Ross, Linda; Chu, S. Haihua; Pikman, Yana; Robichaud, Amanda; Goodale, Amy; Häupl, Björn; Mohr, Sebastian; Rao, Arati V.; Walker, Alison R.; Blachly, James S.; Piccioni, Federica; Armstrong, Scott A.; Byrd, John C.; Oellerich, Thomas; Stegmaier, Kimberly (2020): Resistance Mechanisms to SYK Inhibition in Acute Myeloid Leukemia. In: Cancer Discovery 10 (2), S. 214–231. DOI: 10.1158/2159-8290.CD-19-0209.

Fang, Pan; Ji, Yanlong; Silbern, Ivan; Doebele, Carmen; Ninov, Momchil; Lenz, Christof; Oellerich, Thomas; Pan, Kuan-Ting; Urlaub, Henning (2020): A streamlined pipeline for multiplexed quantitative site-specific N-glycoproteomics. In: Nature Communications 11 (1), S. 5268. DOI: 10.1038/s41467-020-19052-w.

Fish, Kamonwan; Comoglio, Federico; Shaffer, Arthur L. 3rd; Ji, Yanlong; Pan, Kuan-Ting; Scheich, Sebastian; Oellerich, Angelika; Doebele, Carmen; Ikeda, Masato; Schaller, Samantha J.; Nguyen, Hang; Muppidi, Jagan; Wright, George W.; Urlaub, Henning; Serve, Hubert; Staudt, Louis M.; Longnecker, Richard; Oellerich, Thomas (2020): Rewiring of B cell receptor signaling by Epstein-Barr virus LMP2A. In: Proceedings of the National Academy of Sciences of the United States of America 117 (42), S. 26318–26327. DOI: 10.1073/pnas.2007946117.

Frejno, Martin; Meng, Chen; Ruprecht, Benjamin; Oellerich, Thomas; Scheich, Sebastian; Kleigrewe, Karin; Drecoll, Enken; Samaras, Patroklos; Hogrebe, Alexander; Helm, Dominic; Mergner, Julia; Zecha, Jana; Heinzlmeir, Stephanie; Wilhelm, Mathias; Dorn, Julia; Kvasnicka, Hans-Michael; Serve, Hubert; Weichert, Wilko; Kuster, Bernhard (2020): Proteome activity landscapes of tumor cell lines determine drug responses. In: Nature Communications 11 (1), S. 3639. DOI: 10.1038/s41467-020-17336-9.

Godavarthy, Parimala Sonika; Kumar, Rahul; Herkt, Stefanie C.; Pereira, Raquel S.; Hayduk, Nina; Weissenberger, Eva S.; Aggoune, Djamel; Manavski, Yosif; Lucas, Tina; Pan, Kuan-Ting; Voutsinas, Jenna M.; Wu, Qian; Müller, Martin C.; Saussele, Susanne; Oellerich, Thomas; Oehler, Vivian G.; Lausen, Joern; Krause, Daniela S. (2020): The vascular bone marrow niche influences outcome in chronic myeloid leukemia via the E-selectin - SCL/TAL1 - CD44 axis. In: Haematologica 105 (1), S. 136–147. DOI: 10.3324/haematol.2018.212365.

Kumar, Rahul; Pereira, Raquel S.; Zanetti, Costanza; Minciacchi, Valentina R.; Merten, Maximilian; Meister, Melanie; Niemann, Julian; Dietz, Marina S.; Rüssel, Nina; Schnütgen, Frank; Tamai, Minori; Akahane, Koshi; Inukai, Takeshi; Oellerich, Thomas; Kvasnicka, Hans Michael; Pfeifer, Heike; Nicolini, Franck E.; Heilemann, Mike; van Etten, Richard A.; Krause, Daniela S. (2020): Specific, targetable interactions with the microenvironment influence imatinib-resistant chronic myeloid leukemia. In: Leukemia 34 (8), S. 2087–2101. DOI: 10.1038/s41375-020-0866-1.

Meyer, Annekarin; Herkt, Stefanie; Kunze-Schumacher, Heike; Kohrs, Nicole; Ringleb, Julia; Schneider, Lucas; Kuvardina, Olga N.; Oellerich, Thomas; Häupl, Björn; Krueger, Andreas; Seifried, Erhard; Bonig, Halvard; Lausen, Joern (2020): The transcription factor TAL1 and miR-17-92 create a regulatory loop in hematopoiesis. In: Scientific Reports 10 (1), S. 21438. DOI: 10.1038/s41598-020-78629-z.

Rothenburger, Tamara; McLaughlin, Katie-May; Herold, Tobias; Schneider, Constanze; Oellerich, Thomas; Rothweiler, Florian; Feber, Andrew; Fenton, Tim R.; Wass, Mark N.; Keppler, Oliver T.; Michaelis, Martin; Cinatl, Jindrich, JR (2020): SAMHD1 is a key regulator of the lineage-specific response of acute lymphoblastic leukaemias to nelarabine. In: Communications Biology 3 (1), S. 324. DOI: 10.1038/s42003-020-1052-8.

Varga, Julia; Nicolas, Adele; Petrocelli, Valentina; Pesic, Marina; Mahmoud, Abdelrahman; Michels, Birgitta E.; Etlioglu, Emre; Yepes, Diego; Häupl, Björn; Ziegler, Paul K.; Bankov, Katrin; Wild, Peter J.; Wanninger, Stefan; Medyouf, Hind; Farin, Henner F.; Tejpar, Sabine; Oellerich, Thomas; Ruland, Jürgen; Siebel, Christian W.; Greten, Florian R. (2020): AKT-dependent NOTCH3 activation drives tumor progression in a model of mesenchymal colorectal cancer. In: The Journal of Experimental Medicine 217 (10). DOI: 10.1084/jem.20191515.

Walker, Alison R.; Byrd, John C.; Blachly, James S.; Bhatnagar, Bhavana; Mims, Alice S.; Orwick, Shelley; Lin, Tara L.; Crosswell, Howland E.; Zhang, Danjie; Minden, Mark D.; Munugalavadla, Veerendra; Long, Lauren; Liu, Jinfeng; Pan, Yang; Oellerich, Thomas; Serve, Hubert; Rao, Arati V.; Blum, William G. (2020): Entospletinib in Combination with Induction Chemotherapy in Previously Untreated Acute Myeloid Leukemia: Response and Predictive Significance of HOXA9 and MEIS1 Expression. In: Clinical Cancer Research 26 (22), S. 5852–5859. DOI: 10.1158/1078-0432.CCR-20-1064.

Bremmer, Felix; Bohnenberger, Hanibal; Küffer, Stefan; Oellerich, Thomas; Serve, Hubert; Urlaub, Henning; Strauss, Arne; Maatoug, Yasmine; Behnes, Carl Ludwig; Oing, Christoph; Radzun, Heinz Joachim; Ströbel, Philipp; Balabanov, Stefan; Honecker, Friedemann (2019): Proteomic Comparison of Malignant Human Germ Cell Tumor Cell Lines. In: Disease Markers 2019, S. 8298524. DOI: 10.1155/2019/8298524.

Häupl, Björn; Urlaub, Henning; Oellerich, Thomas (2019): Phosphoproteomic Analysis of Signaling Pathways in Lymphomas. In: Methods in Molecular Biology (Clifton, N.J.) 1956, S. 371–381. DOI: 10.1007/978-1-4939-9151-8_19.

Kreitz, Johanna; Schönfeld, Christine; Seibert, Marcel; Stolp, Verena; Alshamleh, Islam; Oellerich, Thomas; Steffen, Björn; Schwalbe, Harald; Schnütgen, Frank; Kurrle, Nina; Serve, Hubert (2019): Metabolic Plasticity of Acute Myeloid Leukemia. In: Cells 8 (8). DOI: 10.3390/cells8080805.

Michels, Birgitta E.; Mosa, Mohammed H.; Grebbin, Britta M.; Yepes, Diego; Darvishi, Tahmineh; Hausmann, Johannes; Urlaub, Henning; Zeuzem, Stefan; Kvasnicka, Hans M.; Oellerich, Thomas; Farin, Henner F. (2019): Human colon organoids reveal distinct physiologic and oncogenic Wnt responses. In: The Journal of Experimental Medicine 216 (3), S. 704–720. DOI: 10.1084/jem.20180823.

Nguyen, The Duy; Shaid, Shabnam; Vakhrusheva, Olesya; Koschade, Sebastian E.; Klann, Kevin; Thölken, Marlyn; Baker, Fatima; Zhang, Jing; Oellerich, Thomas; Sürün, Duran; Derlet, Anja; Haberbosch, Isabella; Eimer, Stefan; Osiewacz, Heinz D.; Behrends, Christian; Münch, Christian; Dikic, Ivan; Brandts, Christian H. (2019): Loss of the selective autophagy receptor p62 impairs murine myeloid leukemia progression and mitophagy. In: Blood 133 (2), S. 168–179. DOI: 10.1182/blood-2018-02-833475.

Oellerich, Thomas; Schneider, Constanze; Thomas, Dominique; Knecht, Kirsten M.; Buzovetsky, Olga; Kaderali, Lars; Schliemann, Christoph; Bohnenberger, Hanibal; Angenendt, Linus; Hartmann, Wolfgang; Wardelmann, Eva; Rothenburger, Tamara; Mohr, Sebastian; Scheich, Sebastian; Comoglio, Federico; Wilke, Anne; Ströbel, Philipp; Serve, Hubert; Michaelis, Martin; Ferreirós, Nerea; Geisslinger, Gerd; Xiong, Yong; Keppler, Oliver T.; Cinatl, Jindrich, JR (2019): Selective inactivation of hypomethylating agents by SAMHD1 provides a rationale for therapeutic stratification in AML. In: Nature Communications 10 (1), S. 3475. DOI: 10.1038/s41467-019-11413-4.

Schroeder, Michael P.; Bastian, Lorenz; Eckert, Cornelia; Gökbuget, Nicola; James, Alva Rani; Tanchez, Jutta Ortiz; Schlee, Cornelia; Isaakidis, Konstandina; Häupl, Björn; Baum, Katharina; Migueles Lozano, Oscar Arturo; Kouidri, Khouloud; Pan, Kuan-Ting; Urlaub, Henning; Schwartz, Stefan; Burmeister, Thomas; Stackelberg, Arend von; Hoelzer, Dieter; Pfeiffer, Heike; Rieger, Michael A.; Göllner, Stefanie; Oellerich, Thomas; Horstman, Martin; Schrappe, Martin; Wolf, Jana; Kirschner-Schwabe, Renate; Brüggemann, Monika; Müller-Tidow, Carsten; Serve, Hubert; Neumann, Martin; Baldus, Claudia D. (2019): Integrated analysis of relapsed B-cell precursor Acute Lymphoblastic Leukemia identifies subtype-specific cytokine and metabolic signatures. In: Scientific Reports 9 (1), S. 4188. DOI: 10.1038/s41598-019-40786-1.

van Hoang, T.; Verma, Divij; Godavarthy, Parimala Sonika; Llavona, Pablo; Steiner, Marlene; Gerlach, Katharina; Michels, Birgitta E.; Bohnenberger, Hanibal; Wachter, Astrid; Oellerich, Thomas; Müller-Kuller, Uta; Weissenberger, Eva; Voutsinas, Jenna M.; Oehler, Vivian G.; Farin, Henner F.; Zörnig, Martin; Krause, Daniela S. (2019): The transcriptional regulator FUBP1 influences disease outcome in murine and human myeloid leukemia. In: Leukemia 33 (7), S. 1700–1712. DOI: 10.1038/s41375-018-0358-8.

Bohnenberger, Hanibal; Kaderali, Lars; Ströbel, Philipp; Yepes, Diego; Plessmann, Uwe; Dharia, Neekesh V.; Yao, Sha; Heydt, Carina; Merkelbach-Bruse, Sabine; Emmert, Alexander; Hoffmann, Jonatan; Bodemeyer, Julius; Reuter-Jessen, Kirsten; Lois, Anna-Maria; Dröge, Leif Hendrik; Baumeister, Philipp; Walz, Christoph; Biggemann, Lorenz; Walter, Roland; Häupl, Björn; Comoglio, Federico; Pan, Kuan-Ting; Scheich, Sebastian; Lenz, Christof; Küffer, Stefan; Bremmer, Felix; Kitz, Julia; Sitte, Maren; Beißbarth, Tim; Hinterthaner, Marc; Sebastian, Martin; Lotz, Joachim; Schildhaus, Hans-Ulrich; Wolff, Hendrik; Danner, Bernhard C.; Brandts, Christian; Büttner, Reinhard; Canis, Martin; Stegmaier, Kimberly; Serve, Hubert; Urlaub, Henning; Oellerich, Thomas (2018): Comparative proteomics reveals a diagnostic signature for pulmonary head-and-neck cancer metastasis. In: EMBO Molecular Medicine 10 (9). DOI: 10.15252/emmm.201708428.

Dietrich, Sascha; Oleś, Małgorzata; Lu, Junyan; Sellner, Leopold; Anders, Simon; Velten, Britta; Wu, Bian; Hüllein, Jennifer; Da Silva Liberio, Michelle; Walther, Tatjana; Wagner, Lena; Rabe, Sophie; Ghidelli-Disse, Sonja; Bantscheff, Marcus; Oleś, Andrzej K.; Słabicki, Mikołaj; Mock, Andreas; Oakes, Christopher C.; Wang, Shihui; Oppermann, Sina; Lukas, Marina; Kim, Vladislav; Sill, Martin; Benner, Axel; Jauch, Anna; Sutton, Lesley Ann; Young, Emma; Rosenquist, Richard; Liu, Xiyang; Jethwa, Alexander; Lee, Kwang Seok; Lewis, Joe; Putzker, Kerstin; Lutz, Christoph; Rossi, Davide; Mokhir, Andriy; Oellerich, Thomas; Zirlik, Katja; Herling, Marco; Nguyen-Khac, Florence; Plass, Christoph; Andersson, Emma; Mustjoki, Satu; Kalle, Christof von; Ho, Anthony D.; Hensel, Manfred; Dürig, Jan; Ringshausen, Ingo; Zapatka, Marc; Huber, Wolfgang; Zenz, Thorsten (2018): Drug-perturbation-based stratification of blood cancer. In: The Journal of Clinical Investigation 128 (1), S. 427–445. DOI: 10.1172/JCI93801.

Phelan, James D.; Young, Ryan M.; Webster, Daniel E.; Roulland, Sandrine; Wright, George W.; Kasbekar, Monica; Shaffer, Arthur L. 3rd; Ceribelli, Michele; Wang, James Q.; Schmitz, Roland; Nakagawa, Masao; Bachy, Emmanuel; Da Huang, Wei; Ji, Yanlong; Chen, Lu; Yang, Yandan; Zhao, Hong; Yu, Xin; Xu, Weihong; Palisoc, Maryknoll M.; Valadez, Racquel R.; Davies-Hill, Theresa; Wilson, Wyndham H.; Chan, Wing C.; Jaffe, Elaine S.; Gascoyne, Randy D.; Campo, Elias; Rosenwald, Andreas; Ott, German; Delabie, Jan; Rimsza, Lisa M.; Rodriguez, Fausto J.; Estephan, Fayez; Holdhoff, Matthias; Kruhlak, Michael J.; Hewitt, Stephen M.; Thomas, Craig J.; Pittaluga, Stefania; Oellerich, Thomas*; Staudt, Louis M.* (2018): A multiprotein supercomplex controlling oncogenic signalling in lymphoma. In: Nature 560 (7718), S. 387–391. DOI: 10.1038/s41586-018-0290-0. (*Equal Contribution and co-corresponding author)

Weßbecher, Isabel M.; Hinrichsen, Inga; Funke, Sebastian; Oellerich, Thomas; Plotz, Guido; Zeuzem, Stefan; Grus, Franz H.; Biondi, Ricardo M.; Brieger, Angela (2018): DNA mismatch repair activity of MutLα is regulated by CK2-dependent phosphorylation of MLH1 (S477). In: Molecular Carcinogenesis 57 (12), S. 1723–1734. DOI: 10.1002/mc.22892.

Arencibia, Jose M.; Fröhner, Wolfgang; Krupa, Magdalena; Pastor-Flores, Daniel; Merker, Piotr; Oellerich, Thomas; Neimanis, Sonja; Schmithals, Christian; Köberle, Verena; Süß, Evelyn; Zeuzem, Stefan; Stark, Holger; Piiper, Albrecht; Odadzic, Dalibor; Schulze, Jörg O.; Biondi, Ricardo M. (2017): An Allosteric Inhibitor Scaffold Targeting the PIF-Pocket of Atypical Protein Kinase C Isoforms. In: ACS Chemical Biology 12 (2), S. 564–573. DOI: 10.1021/acschembio.6b00827.

Göllner, Stefanie; Oellerich, Thomas; Agrawal-Singh, Shuchi; Schenk, Tino; Klein, Hans-Ulrich; Rohde, Christian; Pabst, Caroline; Sauer, Tim; Lerdrup, Mads; Tavor, Sigal; Stölzel, Friedrich; Herold, Sylvia; Ehninger, Gerhard; Köhler, Gabriele; Pan, Kuan-Ting; Urlaub, Henning; Serve, Hubert; Dugas, Martin; Spiekermann, Karsten; Vick, Binje; Jeremias, Irmela; Berdel, Wolfgang E.; Hansen, Klaus; Zelent, Arthur; Wickenhauser, Claudia; Müller, Lutz P.; Thiede, Christian; Müller-Tidow, Carsten (2017): Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia. In: Nature Medicine 23 (1), S. 69–78. DOI: 10.1038/nm.4247.

Mohr, Sebastian; Doebele, Carmen; Comoglio, Federico; Berg, Tobias; Beck, Julia; Bohnenberger, Hanibal; Alexe, Gabriela; Corso, Jasmin; Ströbel, Philipp; Wachter, Astrid; Beissbarth, Tim; Schnütgen, Frank; Cremer, Anjali; Haetscher, Nadine; Göllner, Stefanie; Rouhi, Arefeh; Palmqvist, Lars; Rieger, Michael A.; Schroeder, Timm; Bönig, Halvard; Müller-Tidow, Carsten; Kuchenbauer, Florian; Schütz, Ekkehard; Green, Anthony R.; Urlaub, Henning; Stegmaier, Kimberly; Humphries, R. Keith; Serve, Hubert; Oellerich, Thomas (2017): Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia. In: Cancer Cell 31 (4), 549-562.e11. DOI: 10.1016/j.ccell.2017.03.001.

Schneider, Constanze; Oellerich, Thomas; Baldauf, Hanna-Mari; Schwarz, Sarah-Marie; Thomas, Dominique; Flick, Robert; Bohnenberger, Hanibal; Kaderali, Lars; Stegmann, Lena; Cremer, Anjali; Martin, Margarethe; Lohmeyer, Julian; Michaelis, Martin; Hornung, Veit; Schliemann, Christoph; Berdel, Wolfgang E.; Hartmann, Wolfgang; Wardelmann, Eva; Comoglio, Federico; Hansmann, Martin-Leo; Yakunin, Alexander F.; Geisslinger, Gerd; Ströbel, Philipp; Ferreirós, Nerea; Serve, Hubert; Keppler, Oliver T.; Cinatl, Jindrich, JR (2017): Corrigendum: SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia. In: Nature Medicine 23 (6), S. 788. DOI: 10.1038/nm0617-788a.

Schneider, Constanze*; Oellerich, Thomas*; Baldauf, Hanna-Mari*; Schwarz, Sarah-Marie*; Thomas, Dominique; Flick, Robert; Bohnenberger, Hanibal; Kaderali, Lars; Stegmann, Lena; Cremer, Anjali; Martin, Margarethe; Lohmeyer, Julian; Michaelis, Martin; Hornung, Veit; Schliemann, Christoph; Berdel, Wolfgang E.; Hartmann, Wolfgang; Wardelmann, Eva; Comoglio, Federico; Hansmann, Martin-Leo; Yakunin, Alexander F.; Geisslinger, Gerd; Ströbel, Philipp; Ferreirós, Nerea; Serve, Hubert; Keppler, Oliver T.; Cinatl, Jindrich, JR (2017): SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia. In: Nature Medicine 23 (2), S. 250–255. DOI: 10.1038/nm.4255. (*Equal Contribution)

Shafat, Manar S.; Oellerich, Thomas; Mohr, Sebastian; Robinson, Stephen D.; Edwards, Dylan R.; Marlein, Christopher R.; Piddock, Rachel E.; Fenech, Matthew; Zaitseva, Lyubov; Abdul-Aziz, Amina; Turner, Jeremy; Watkins, Johnathan A.; Lawes, Matthew; Bowles, Kristian M.; Rushworth, Stuart A. (2017): Leukemic blasts program bone marrow adipocytes to generate a protumoral microenvironment. In: Blood 129 (10), S. 1320–1332. DOI: 10.1182/blood-2016-08-734798.

Walter, Roland; Pan, Kuan-Ting; Doebele, Carmen; Comoglio, Federico; Tomska, Katarzyna; Bohnenberger, Hanibal; Young, Ryan M.; Jacobs, Laura; Keller, Ulrich; Bönig, Halvard; Engelke, Michael; Rosenwald, Andreas; Urlaub, Henning; Staudt, Louis M.; Serve, Hubert; Zenz, Thorsten; Oellerich, Thomas (2017): HSP90 promotes Burkitt lymphoma cell survival by maintaining tonic B-cell receptor signaling. In: Blood 129 (5), S. 598–608. DOI: 10.1182/blood-2016-06-721423.

Zhou, Fengbiao; Liu, Yi; Rohde, Christian; Pauli, Cornelius; Gerloff, Dennis; Köhn, Marcel; Misiak, Danny; Bäumer, Nicole; Cui, Chunhong; Göllner, Stefanie; Oellerich, Thomas; Serve, Hubert; Garcia-Cuellar, Maria-Paz; Slany, Robert; Maciejewski, Jaroslaw P.; Przychodzen, Bartlomiej; Seliger, Barbara; Klein, Hans-Ulrich; Bartenhagen, Christoph; Berdel, Wolfgang E.; Dugas, Martin; Taketo, Makoto Mark; Farouq, Daneyal; Schwartz, Schraga; Regev, Aviv; Hébert, Josée; Sauvageau, Guy; Pabst, Caroline; Hüttelmaier, Stefan; Müller-Tidow, Carsten (2017): AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia. In: Nature Cell Biology 19 (7), S. 844–855. DOI: 10.1038/ncb3563.

Corso, Jasmin; Pan, Kuan-Ting; Walter, Roland; Doebele, Carmen; Mohr, Sebastian; Bohnenberger, Hanibal; Ströbel, Philipp; Lenz, Christof; Slabicki, Mikolaj; Hüllein, Jennifer; Comoglio, Federico; Rieger, Michael A.; Zenz, Thorsten; Wienands, Jürgen; Engelke, Michael; Serve, Hubert; Urlaub, Henning; Oellerich, Thomas (2016): Elucidation of tonic and activated B-cell receptor signaling in Burkitt's lymphoma provides insights into regulation of cell survival. In: Proceedings of the National Academy of Sciences of the United States of America 113 (20), S. 5688–5693. DOI: 10.1073/pnas.1601053113.

Hacken, Elisa ten; Sivina, Mariela; Kim, Ekaterina; O'Brien, Susan; Wierda, William G.; Ferrajoli, Alessandra; Estrov, Zeev; Keating, Michael J.; Oellerich, Thomas; Scielzo, Cristina; Ghia, Paolo; Caligaris-Cappio, Federico; Burger, Jan A. (2016): Functional Differences between IgM and IgD Signaling in Chronic Lymphocytic Leukemia. In: Journal of Immunology (Baltimore, Md. : 1950) 197 (6), S. 2522–2531. DOI: 10.4049/jimmunol.1600915.

Helmke, Christina; Raab, Monika; Rödel, Franz; Matthess, Yves; Oellerich, Thomas; Mandal, Ranadip; Sanhaji, Mourad; Urlaub, Henning; Rödel, Claus; Becker, Sven; Strebhardt, Klaus (2016): Ligand stimulation of CD95 induces activation of Plk3 followed by phosphorylation of caspase-8. In: Cell Research 26 (8), S. 914–934. DOI: 10.1038/cr.2016.78.

Manno, Birgit; Oellerich, Thomas; Schnyder, Tim; Corso, Jasmin; Lösing, Marion; Neumann, Konstantin; Urlaub, Henning; Batista, Facundo D.; Engelke, Michael; Wienands, Jürgen (2016): The Dok-3/Grb2 adaptor module promotes inducible association of the lipid phosphatase SHIP with the BCR in a coreceptor-independent manner. In: European Journal of Immunology 46 (11), S. 2520–2530. DOI: 10.1002/eji.201646431.

Bohnenberger, Hanibal; Ströbel, Philipp; Mohr, Sebastian; Corso, Jasmin; Berg, Tobias; Urlaub, Henning; Lenz, Christof; Serve, Hubert; Oellerich, Thomas (2015): Quantitative mass spectrometric profiling of cancer-cell proteomes derived from liquid and solid tumors. In: Journal of Visualized Experiments : JoVE (96), e52435. DOI: 10.3791/52435.

Haetscher, Nadine; Feuermann, Yonatan; Wingert, Susanne; Rehage, Maike; Thalheimer, Frederic B.; Weiser, Christian; Bohnenberger, Hanibal; Jung, Klaus; Schroeder, Timm; Serve, Hubert; Oellerich, Thomas; Hennighausen, Lothar; Rieger, Michael A. (2015): STAT5-regulated microRNA-193b controls haematopoietic stem and progenitor cell expansion by modulating cytokine receptor signalling. In: Nature Communications 6, S. 8928. DOI: 10.1038/ncomms9928.

Kuvardina, Olga N.; Herglotz, Julia; Kolodziej, Stephan; Kohrs, Nicole; Herkt, Stefanie; Wojcik, Bartosch; Oellerich, Thomas; Corso, Jasmin; Behrens, Kira; Kumar, Ashok; Hussong, Helge; Urlaub, Henning; Koch, Joachim; Serve, Hubert; Bonig, Halvard; Stocking, Carol; Rieger, Michael A.; Lausen, Jörn (2015): RUNX1 represses the erythroid gene expression program during megakaryocytic differentiation. In: Blood 125 (23), S. 3570–3579. DOI: 10.1182/blood-2014-11-610519.

Lugassy, Jennie; Corso, Jasmin; Beach, Dvora; Petrik, Thomas; Oellerich, Thomas; Urlaub, Henning; Yablonski, Deborah (2015): Modulation of TCR responsiveness by the Grb2-family adaptor, Gads. In: Cellular Signalling 27 (1), S. 125–134. DOI: 10.1016/j.cellsig.2014.10.005.

Oellerich, Thomas; Mohr, Sebastian; Corso, Jasmin; Beck, Julia; Döbele, Carmen; Braun, Helene; Cremer, Anjali; Münch, Silvia; Wicht, Johannes; Oellerich, Mark F.; Bug, Gesine; Bohnenberger, Hanibal; Perske, Christina; Schütz, Ekkehard; Urlaub, Henning; Serve, Hubert (2015): FLT3-ITD and TLR9 use Bruton tyrosine kinase to activate distinct transcriptional programs mediating AML cell survival and proliferation. In: Blood 125 (12), S. 1936–1947. DOI: 10.1182/blood-2014-06-585216.

Yang, Chul Min; Chiba, Tomohiro; Brill, Boris; Delis, Natalia; Manstein, Viktoria von; Vafaizadeh, Vida; Oellerich, Thomas; Groner, Bernd (2015): Expression of the miR-302/367 cluster in glioblastoma cells suppresses tumorigenic gene expression patterns and abolishes transformation related phenotypes. In: International Journal of Cancer 137 (10), S. 2296–2309. DOI: 10.1002/ijc.29606.

Berg, Tobias; Thoene, Silvia; Yap, Damian; Wee, Tracee; Schoeler, Nathalie; Rosten, Patty; Lim, Emilia; Bilenky, Misha; Mungall, Andrew J.; Oellerich, Thomas; Lee, Sherry; Lai, Courteney K.; Umlandt, Patricia; Salmi, Anisa; Chang, Harry; Yue, Lisa; Lai, David; Cheng, S-W Grace; Morin, Ryan D.; Hirst, Martin; Serve, Hubert; Marra, Marco A.; Morin, Gregg B.; Gascoyne, Randy D.; Aparicio, Samuel A.; Humphries, R. Keith (2014): A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis. In: Blood 123 (25), S. 3914–3924. DOI: 10.1182/blood-2012-12-473439.

Kolodziej, Stephan; Kuvardina, Olga N.; Oellerich, Thomas; Herglotz, Julia; Backert, Ingo; Kohrs, Nicole; La Buscató, Estel; Wittmann, Sandra K.; Salinas-Riester, Gabriela; Bonig, Halvard; Karas, Michael; Serve, Hubert; Proschak, Ewgenij; Lausen, Jörn (2014): PADI4 acts as a coactivator of Tal1 by counteracting repressive histone arginine methylation. In: Nature Communications 5, S. 3995. DOI: 10.1038/ncomms4995.

Castello, Angelo; Gaya, Mauro; Tucholski, Johannes; Oellerich, Thomas; Lu, Kun-Hui; Tafuri, Anna; Pawson, Tony; Wienands, Jürgen; Engelke, Michael; Batista, Facundo D. (2013): Nck-mediated recruitment of BCAP to the BCR regulates the PI(3)K-Akt pathway in B cells. In: Nature Immunology 14 (9), S. 966–975. DOI: 10.1038/ni.2685.

Engelke, Michael; Oellerich, Thomas; Dittmann, Kai; Hsiao, He-Hsuan; Urlaub, Henning; Serve, Hubert; Griesinger, Christian; Wienands, Jürgen (2013): Cutting edge: feed-forward activation of phospholipase Cγ2 via C2 domain-mediated binding to SLP65. In: Journal of Immunology (Baltimore, Md. : 1950) 191 (11), S. 5354–5358. DOI: 10.4049/jimmunol.1301326.

Lösing, Marion; Goldbeck, Ingo; Manno, Birgit; Oellerich, Thomas; Schnyder, Tim; Bohnenberger, Hanibal; Stork, Björn; Urlaub, Henning; Batista, Facundo D.; Wienands, Jürgen; Engelke, Michael (2013): The Dok-3/Grb2 protein signal module attenuates Lyn kinase-dependent activation of Syk kinase in B cell antigen receptor microclusters. In: The Journal of Biological Chemistry 288 (4), S. 2303–2313. DOI: 10.1074/jbc.M112.406546.

Oellerich, Thomas; Oellerich, Mark F.; Engelke, Michael; Münch, Silvia; Mohr, Sebastian; Nimz, Marika; Hsiao, He-Hsuan; Corso, Jasmin; Zhang, Jing; Bohnenberger, Hanibal; Berg, Tobias; Rieger, Michael A.; Wienands, Jürgen; Bug, Gesine; Brandts, Christian; Urlaub, Henning; Serve, Hubert (2013): β2 integrin-derived signals induce cell survival and proliferation of AML blasts by activating a Syk/STAT signaling axis. In: Blood 121 (19), 3889-99, S1-66. DOI: 10.1182/blood-2012-09-457887.

Batsukh, Tserendulam; Schulz, Yvonne; Wolf, Stephan; Rabe, Tamara I.; Oellerich, Thomas; Urlaub, Henning; Schaefer, Inga-Marie; Pauli, Silke (2012): Identification and characterization of FAM124B as a novel component of a CHD7 and CHD8 containing complex. In: PloS one 7 (12), e52640. DOI: 10.1371/journal.pone.0052640.

Bohnenberger, Hanibal; Oellerich, Thomas; Engelke, Michael; Hsiao, He-Hsuan; Urlaub, Henning; Wienands, Jürgen (2011): Complex phosphorylation dynamics control the composition of the Syk interactome in B cells. In: European Journal of Immunology 41 (6), S. 1550–1562. DOI: 10.1002/eji.201041326.

Neumann, Konstantin; Oellerich, Thomas; Heine, Ines; Urlaub, Henning; Engelke, Michael (2011): Fc gamma receptor IIb modulates the molecular Grb2 interaction network in activated B cells. In: Cellular Signalling 23 (5), S. 893–900. DOI: 10.1016/j.cellsig.2011.01.015.

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