
FOR5643
HERZBLUT
Projects
FOR5643
HERZBLUT
Projects

FOR5643 HERZBLUT
PROJECTS
PROJECTS

A1
Interaction of clonal hematopoiesis-driver mutations with heart failure


Stefanie Dimmeler/Andreas Zeiher
A2
Mechanisms of aortic valve calcification driven by clonal hematopoiesis mutations


Wesley Abplanalp/Silvia Mas-Peiro
A3
Epigenetic-metabolic contribution to inflammatory phenotypes of CH in pulmonary hypertension


Soni Savai Pullamsetti
A4
In vitro CHIP modelling for therapeutics discovery and mechanistic dissection


Jaya Krishnan
A5
Identification and targeting of mutated PPM1D for preventing cardiovascular events and therapy-related myeloid neoplasms in cancer survivors


Anjali Cremer
B1
Comparative functional characterization of distinct CH mutations recurrent in cardiovascular disease and myeloid malignancies


Hubert Serve/Frank Schnütgen
B2
Quantitative assessment of clonal architecture, stem cell competition and lineage fate in CH

Michael Rieger
B3
Acceleration of clonal hematopoiesis mediated by the bone marrow niche in heart failure


Sebastian Cremer/Konstantinos Kokkaliaris
B4
Rewiring leukemogenic transformation of GATA1s-mediated CH by KANSL1 loss-of-function mutations


Jan-Henning Klusmann/Marit Vermunt